Dr. Muhammad Rehan Uppal

In 2004, Dr. Rehan Uppal co-founded the Islamabad Diagnostic Centre (IDC), now one of Pakistan's leading diagnostic networks.

IDC includes:

• 170+ branches across 65+ cities
• 4,000+ staff and 300+ doctors
• 4 million patients & 10 million tests annually
• Comprehensive laboratory & advanced imaging services
• FCPS-recognised training in radiology and laboratory medicine

IDC is recognised for its accuracy, reliability and timely reporting, while also contributing to medical education, research and the training of future healthcare professionals in Pakistan.

Early in his career, Dr. Rehan Uppal served as a designated physician to several diplomatic missions in Islamabad, including the U.S. Embassy and the Embassy of Russia.

During the COVID-19 pandemic, Dr. Uppal played an active role in clinical care and led diagnostic support efforts through IDC, contributing to nationwide testing and public awareness initiatives.

Dr. Rehan Uppal believes in an evidence-based, patient-centred approach to care. Where appropriate, he integrates complementary therapies, including homeopathy, with conventional medical treatment to provide personalised care.

Every treatment plan is tailored to the patient's individual needs, with a focus on ethical practice, long-term health, and overall wellbeing.

Alongside his clinical practice, Dr. Rehan Uppal is actively involved in clinical research with publications in national and international journals.

His research includes:

• Pharmacological SIRT1 Inhibition Exacerbates Angiotensin II-InducedMyocardial Injury and Is Associated with Dysregulation of the p53-FOXO3a Stress-Response Axis
• Temporal Distribution of Elevated-HbA1c Records and a Young-Adult Multiorgan Biomarker Profile in Diabetes: A Retrospective Observational Study
• The Resistance Constellation Across the Sepsis–Uropathogen Continuum: A Thirteen-Year Atlas of Epidemiological Expansion, Resistance Kinetics, and Progressive Therapeutic Attrition
• Ten-year trends in sepsis-causing multidrug-resistant pathogens: a nationwide multicenter laboratory-based surveillance in Pakistan (2013–2022) and predictive forecasting of antimicrobial resistance (2030)
• Pro-brain natriuretic peptide, HbA1c, and C-Reactive protein unveil a distinct inflammatory–glycemic–cardiorenal signature associated with hepatitis B virus infection in diabetic kidney disease
• Fosfomycin Resistance Dynamics in Major Uropathogens: A 2013–2025 Integrated Disease Surveillance of Multidrug-Resistant, Extended-Spectrum Beta-Lactamase-Producing, Non-Extended-Spectrum Beta-Lactamase, and Enterococcal Urinary Isolates
• Interval reduction in MRI lesion burden in relapsing-remitting multiple sclerosis following an integrative alternative medicine regimen: a case report
• Hepatitis B virus in Pakistan: serological marker prevalence, clinical correlates, and genotype-informed interpretation
• Exploring the impact of glycemic control on renal, hepatic, and lipid biomarkers in diabetic patients: a retrospective laboratory analysis from 2019 to 2022
• Therapeutic Breakthrough in Chronic Migraine Management: Clinical Efficacy of Individualized Classical Homeopathic Treatment in a Two-Year, Double-Blind, Placebo-Controlled Multicenter Study on 100 Adults
• Evaluation of a new glucometer compared to a trusted lab method: improving accuracy in diabetes monitoring: Evaluation of Novel Glucometer in Pakistan
• Bridging the gap between point-of-care and laboratory standards: comparative evaluation of MedSenso and DSA glucometers against Cobas analyzers for accurate diabetes monitoring
• Estimating high mobility group box protein 1 (HMGB1) single nucleotide polymorphisms among hepatitis B virus infected patients of Pakistan origin
• Lymphopenia as a diagnostic biomarker in clinical COVID-19: insights from a comprehensive study on SARS-CoV-2 variants
• Bacterial infections and antimicrobial resistance patterns: a comprehensive analysis of health dynamics across regions in Pakistan (2013-2023)
• Harnessing Multi-Vitamin Power to Fortify Immune Defense Against SARS-CoV-2: An Evidence-Based Review
• Epidemiological Analysis of Dengue Fever: Insights from Demographic, Serological, and Temporal Data in Pakistan
• Prevalence of Hepatitis C Virus (HCV) Across Age and Gender in a Sample Population: A Cross-Sectional Study in Pakistan
• Paget’s Disease of the Breast, underlying breast cancer mimicking as Benign Dermatological Conditions: Clinical Challenges and Diagnostic Considerations
• Precocious Puberty Induced by Chronic Rhinosinusitis
• Navigating Growing Pains in Pediatric Emergency Care: New Perspectives and Emerging Challenges
• Infecções bacterianas e padrões de resistência antimicrobiana: um estudo abrangente da dinâmica da saúde nas regiões do Paquistão (2013-2023)
• Diminuindo a lacuna entre os padrões de ponto de atendimento e de laboratório: avaliação comparativa dos glicosímetros MedSenso e DSA com os analisadores Cobas para monitoramento preciso do diabetes
• Linfopenia como biomarcador diagnóstico na COVID-19 clínica: evidências de um estudo abrangente sobre variantes do SARS-CoV-2
• Estimativa de polimorfismos de nucleotídeo único da proteína 1 do grupo de alta mobilidade (HMGB1) entre pacientes infectados pelo vírus da hepatite B de origem paquistanesa
• UTERINE GOSSYPIBOMA-A BY PRODUCT RESIDUE OF THE CESAREAN.
• UTERINE GOSSIPYBOMA-A BYPRODUCT OF CAESARIAN
• Unveiling diagnostic prowess: a comparative study of exercise treadmill test and CT coronary in coronary artery disease detection in Pakistan (2021-2023)
• SARS-CoV-2 clearance in term of Cycle Threshold (Ct) during first two waves of COVID-19 in Pakistan: a phenomenon of delayed viral clearance post-corticosteroid treatment
• Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
• Cutting-edge: bionanomaterial solutions in the battle against Severe Acute Respiratory Syndrome Coronavirus 2
• Análise epidemiológica da prevalência da Leishmaniose no Paquistão durante 2016-2023
• Prevalence and clinical profile of hepatitis C virus infections in multitransfused thalassemic patients in the capital twin cities of Pakistan
• Epidemiological analysis of Leishmaniasis prevalence in Pakistan during 2016-2023
• Prevalência e perfil clínico de infecções pelo vírus da hepatite C em pacientes talassêmicos multitransfundidos nas cidades gêmeas capital do Paquistão
• Vanguarda: soluções de bionanomateriais na batalha contra a Síndrome Respiratória Aguda Grave Coronavírus 2
• Revelando proezas diagnósticas: um estudo comparativo entre teste de esforço em esteira e tomografia computadorizada coronária na detecção de doença arterial coronariana no Paquistão (2021-2023)
• Eliminação do SARS-CoV-2 em termos de limite de ciclo (Ct) durante as duas primeiras ondas de COVID-19 no Paquistão: um fenômeno de eliminação viral retardada pós-tratamento com corticosteroides
• Avaliação analítica da sensibilidade e especificidades clínicas de kits de teste de swab nasofaríngeo para detecção rápida de SARS-CoV-2 no Paquistão
• “ALT, AST, GGT, Bili T, HB, HBA1C, CREAT, PT, aPPT, AFP, CEA, CA 125, CA 125, CA 19-9”: biomarcadores iPTH associados ao vírus da hepatite C, tomografia computadorizada e carga de doença do VHC durante a era pré-COVID-19 (2018-2019) e era pós-COVID-19 (2020-2022) no Paquistão
• Antimicrobial susceptibility and clinical characteristics of multidrug-resistant polymicrobial infections in Pakistan, a retrospective study 2019–2021
• Quantitative computed tomography is a novel diagnostic tool for early scrutiny of osteopenia and/or osteoporosis
• Comprehensive clinical insights to diabetic retinopathy in Pakistan: examining prevalence, identifying risk factors, and analyzing visual health patterns
• Hepatitis C virus associated ALT, AST, GGT, Bili T, HB, HBA1C, CREAT, PT, aPPT, AFP, CEA, CA 125, CA 19-9, iPTH biomarkers, computed tomography and HCV burden of disease during pre COVID-19 era (2018-2019) and post COVID-19 era (2020-2022) in Pakistan
• Delving into the impact of cytogenetics and karyotyping on precise diagnosis and quality of life preservation in Pakistan (2011-2022)
• Comparative analysis and predictive modeling of hematologic β-thalassemia minor in Pakistan: a cross-sectional study from 2019-2021
• Rising Surge of Antimicrobial Resistance and Urinary Tract Infections in Pakistani Children: A Potential Life Threating Scenario
• Impact of SARS-CoV-2 on onset of diabetes and associated complications
• Seroprevalence of Hepatitis B virus in multitransfused beta-thalassemic patients in Pakistan
• Reinforced sputnik-v induced spike protein antibody levels in Pakistan: an edge of sputnik-V over sinopharm and SinoVac as commercially available COVID-19 Vaccines
• Effectivity analysis of COVID-19 vaccines against emerging variants of SARS-CoV-2
• SARS-CoV-2-Associated CRP, DD, FER, HBA1c, IL6, LDH, PBNP, and PCT Biomarkers and High-Resolution Computed Tomography During the First Three Waves of COVID-19 in Pakistan (2019-2021)
• SARS-CoV-2 spike antibody levels trend among sinopharm vaccinated people
• Estimating SARS-CoV-2 Spike Antibody Levels Among Sputnik V First Dose Vaccinated People in Pakistan: Formulation of Anti-COVID-19 National Mass Vaccination Strategy.
• Evaluation of SARS-CoV-2 spike antibody levels among Sputnik V first dose vaccinated people in Pakistan: formulation of national anti-COVID-19 mass vaccination strategy.
• SARSCoV-2 related HIV, HBV, RSV, VZV, Enteric viruses, Infl uenza, DENV, S. aureus and TB coinfections
• Laparoscopic liver surgery program: An early experience from an Indian centre
• Bonde mineral density in females and its association with age and vitamin D levels
• Vitamin D Status in Females of Urban Population
• Evaluation of Routine Biomarkers for Identifying Mody in Young-Onset Diabetes: A Retrospective Study from Pakistan Cohort
• Comparative analysis and predictive modeling of hematologic β-thalassemia minor in Pakistan
• Celiac Disease in Pakistan: Transforming Pediatric Diagnosis and Outcomes Through Multi-Marker Serological Screening